Challenge Grants allow SU2C to support a range of new ideas and then support development of the most promising. These programs support investigations of novel or repurposed therapies or screening approaches that have the potential to significantly impact cancer patients in the near term. In the first round of funding, teams are supported to conduct short term, proof of principle projects. Successful research teams will be eligible to apply for additional funding for further studies to bring transformational new options to the clinic. Challenge Grant programs may focus on a particular cancer type or treatment/screening approach.